Table 3.
Effect of Alcohol consumption on all-cause mortality in patients with Non-alcoholic Fatty Liver Disease (NAFLD) according to risk of liver fibrosis.
| NAFLD with low fibrosis risk† (N=3612) |
NAFLD with high fibrosis risk† (N=328) |
|||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| 0.5 -1.4 drinks/day* | 0.46 (0.26-0.81) | 0.007 | 0.64 (0.29-1.35) | 0.241 |
| ≥1.5 drinks/day* | 1.42 (0.92-2.18) | 0.112 | 1.08 (0.51-2.28) | 0.839 |
| Age | 1.09 (1.08-1.10) | <0.001 | 1.11 (1.07-1.14) | <0.001 |
| Male sex | 1.72 (1.23-2.42) | 0.002 | 1.23 (0.75-2.03) | 0.419 |
| Current smoking | 2.35 (1.61-3.45) | <0.001 | 1.68 (0.70-4.05) | 0.244 |
Low fibrosis risk defined as FIB-4< 1.79 and high fibrosis risk defined as FIB-4> 1.79.
Compared to non-drinkers (average of <0.5 drink/day)