Table 6.

Final overall global improvement by demographic characteristic (physician’s assessment) (efficacy analysis population)

Items	Number of patients by characteristic	Improved patients		Unchanged patients		Deteriorated patients
		N	%	N	%	N	%
Overall	2439	1806	74.0	542	22.2	91	3.7
Sex
Male	943	686	72.7	218	23.1	39	4.1
Female	1496	1120	74.9	324	21.7	52	3.5
Age group 1 (years)
< 65	997	731	73.3	226	22.7	40	4.0
≥ 65	1442	1075	74.5	316	21.9	51	3.5
Age group 2 (years)
< 65	997	731	73.3	226	22.7	40	4.0
≥ 65 to < 75	565	417	73.8	128	22.7	20	3.5
≥ 75	877	658	75.0	188	21.4	31	3.5
Age group 3 (years)
< 65	997	731	73.3	226	22.7	40	4.0
≥ 65 to < 85	1213	898	74.0	273	22.5	42	3.5
≥ 85	229	177	77.3	43	18.8	9	3.9
BMI (kg/m2)
< 25.0	1046	782	74.8	233	22.3	31	3.0
≥ 25.0	377	276	73.2	82	21.8	19	5.0
Unknown	1016	748	73.6	227	22.3	41	4.0
Reason for use (multi-count)
Difficulty falling asleep	1826	1356	74.3	410	22.5	60	3.3
Nocturnal awakening	1222	908	74.3	262	21.4	52	4.3
Early morning awakening	261	190	72.8	59	22.6	12	4.6
Others	22	16	72.7	5	22.7	1	4.5
Duration of insomnia (years)
< 1	968	756	78.1	189	19.5	23	2.4
≥ 1 to < 10	1124	814	72.4	262	23.3	48	4.3
≥ 10	347	236	68.0	91	26.2	20	5.8
Medical examinationa
Psychiatry	689	492	71.4	167	24.2	30	4.4
Internal medicine	1515	1139	75.2	320	21.1	56	3.7
Others	235	175	74.5	55	23.4	5	2.1
Narcolepsy-like events
No	2344	1746	74.5	513	21.9	85	3.6
Yes	63	43	68.3	16	25.4	4	6.3
Unknown	32	17	53.1	13	40.6	2	6.3
Diagnosis of narcolepsy (including cataplexy)
No	2404	1784	74.2	531	22.1	89	3.7
Suspected	2	1	50.0	1	50.0	0	0.0
Yes	1	0	0.0	1	100.0	0	0.0
Unknown	32	21	65.6	9	28.1	2	6.3
Respiratory dysfunction
No	2151	1611	74.9	461	21.4	79	3.7
Yes	102	78	76.5	22	21.6	2	2.0
Unknown	186	117	62.9	59	31.7	10	5.4
Chronic obstructive pulmonary disease (COPD)
No	2306	1711	74.2	508	22.0	87	3.8
Yes	44	37	84.1	7	15.9	0	0.0
Unknown	89	58	65.2	27	30.3	4	4.5
Obstructive sleep apnea (OSA)
No	2197	1647	75.0	471	21.4	79	3.6
Yes	60	43	71.7	15	25.0	2	3.3
Unknown	182	116	63.7	56	30.8	10	5.5
Severe respiratory dysfunction
No	2230	1670	74.9	479	21.5	81	3.6
Yes	23	19	82.6	4	17.4	0	0.0
Unknown	186	117	62.9	59	31.7	10	5.4
Hepatic function disorder
No	2254	1680	74.5	491	21.8	83	3.7
Yes	106	75	70.8	27	25.5	4	3.8
Unknown	79	51	64.6	24	30.4	4	5.1
Severe hepatic function disorder
No	2356	1752	74.4	517	21.9	87	3.7
Yes	4	3	75.0	1	25.0	0	0.0
Unknown	79	51	64.6	24	30.4	4	5.1
Structural brain disorder
No	2357	1740	73.8	529	22.4	88	3.7
Yes	82	66	80.5	13	15.9	3	3.7
Psychiatric disorder
No	1642	1246	75.9	343	20.9	53	3.2
Yes	756	534	70.6	185	24.5	37	4.9
Unknown	41	26	63.4	14	34.1	1	2.4
Schizophrenia
No	2321	1728	74.5	507	21.8	86	3.7
Yes	76	52	68.4	21	27.6	3	3.9
Unknown	42	26	61.9	14	33.3	2	4.8
Depression
No	2012	1500	74.6	441	21.9	71	3.5
Yes	386	280	72.5	87	22.5	19	4.9
Unknown	41	26	63.4	14	34.1	1	2.4
Manic-depressive illness
No	2333	1742	74.7	505	21.6	86	3.7
Yes	64	38	59.4	23	35.9	3	4.7
Unknown	42	26	61.9	14	33.3	2	4.8
Anxiety disorder
No	2243	1669	74.4	492	21.9	82	3.7
Yes	154	111	72.1	36	23.4	7	4.5
Unknown	42	26	61.9	14	33.3	2	4.8
Dementia
No	2279	1692	74.2	505	22.2	82	3.6
Yes	118	88	74.6	23	19.5	7	5.9
Unknown	42	26	61.9	14	33.3	2	4.8
Medical history
No	1875	1398	74.6	413	22.0	64	3.4
Yes	403	286	71.0	98	24.3	19	4.7
Unknown	161	122	75.8	31	19.3	8	5.0
Prior medication
No	1446	1136	78.6	281	19.4	29	2.0
Yes	976	659	67.5	256	26.2	61	6.3
Unknown	17	11	64.7	5	29.4	1	5.9
Concomitant medication
No	727	572	78.7	136	18.7	19	2.6
Yes	1695	1223	72.2	401	23.7	71	4.2
Unknown	17	11	64.7	5	29.4	1	5.9
Concomitant insomnia medication
No	1756	1336	76.1	364	20.7	56	3.2
Yes	666	459	68.9	173	26.0	34	5.1
Unknown	17	11	64.7	5	29.4	1	5.9
Initiation status
Naïve	1446	1136	78.6	281	19.4	29	2.0
Switch	538	344	63.9	151	28.1	43	8.0
Add-on	410	292	71.2	101	24.6	17	4.1
Others	45	34	75.6	9	20.0	2	4.4

Totals will not be 100% due to rounding

BMI body mass index

^aPsychiatric and psychosomatic medicines are given as ‘psychiatry’