Table 1.

Atoh1 expression and its function in cell types other than hair cells

Cell type	Function of Atoh1	Phenotype in loss-of-function assays	Reference
Cerebellar granule cells	Maturation and proliferation	Missing external germinal layer (EGL) of the developing cerebellum	Ben-Arie et al., 1997; Wang et al., 2005; Flora et al., 2007; Forget et al., 2014
Retrotrapezoid nucleus (RTN) neurons of the medulla	Migration of neurons and establishment of essential connections with the pre-Bötzinger complex	RTN neurons fail to develop and establish connections with the respiratory rhythm-generating center in mammals	Rose et al., 2009; Huang et al., 2012; Ruffault et al., 2015
D1 commissural interneurons of the spinal cord	Ventral migration and fate determination of D1 interneurons	Progenitors adopting roof plate or D2 interneuron fates	Miesegaes et al., 2009
Intestinal goblet cells	Secretory lineage fate determination	Failure to form intestinal secretory cells	Yang et al., 2001; Shroyer et al., 2007; VanDussen and Samuelson, 2010
Merkel cells	Specification of Merkel cells	Absence of Merkel cells	Ben-Arie et al., 2000; Morrison et al., 2009; van Keymeulen et al., 2009; Maksimovic et al., 2014