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. 2019 Feb 13;7:23. doi: 10.3389/fchem.2019.00023

Figure 9.

Figure 9

The effects of peptides 1, 5, and 6 on prevention of PTB. (A) Schematic of the CD-1 mouse PTB model. In brief, pregnant dams on day 16.5 of gestation (G16.5) were subcutaneously pretreated with peptides 1, 5, and 6 or vehicle, followed by LPS, and observed for delivery of pups. A dam was considered as delivering preterm if at least one pup was delivered before G18.5. (B) The rates of PTB in dams treated with peptides 1, 5, and 6 are grouped into (3R)- (left) and (3S)- (right) derivatives; n = 4–5 dams per treatment group.