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. 2019 Feb 19;9:2249. doi: 10.1038/s41598-019-38680-x

Table 1.

Species-specific missense mutations of positively selected genes.

Species Genes Mutation sites (human) Amino acids (raptors/human) Polarity PolyPhen-2
HumanDiv HumanVar
Accipitrids XRCC5 104 K(Lys)/Q(Gln) polar/polar 0.27 benign 0.055 benign
163 I(Ile)/F(Phe) unpolar/unpolar 0.89 possibly damaging 0.557 possibly damaging
178 V(Val)/R(Arg) unpolar/polar 0.047 benign 0.083 benign
389 A(Ala)/M(Met) unpolar/unpolar 0.937 possibly damaging 0.967 probably damaging
691 T(Thr)/A(Ala) polar/unpolar 0.919 possibly damaging 0.312 benign
Owls ALCAM 259 I(Ile)/A(Ala) unpolar/unpolar 0.617 possibly damaging 0.336 benign
297 M(Met)/T(Thr) unpolar/polar 0.85 possibly damaging 0.557 possibly damaging