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. 2019 Feb 19;9:2269. doi: 10.1038/s41598-019-38785-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The frequency of regulatory T-cells and MDSC in peripheral blood before and after liver resection. (a) The frequency of regulatory T-cells was 2.26 (0.67–6.93)% before liver resection, 1.95 (0.28–4.16)% at one week after liver resection and 2.64 (1.49–4.59)% at one month after liver resection (p = 0.165). The frequency of MDSC was not significantly changed before or after liver resection, either. The median (IQ) frequency of MDSC was 2.40 (0.96–5.65) % before liver resection, compared to 1.93 (0.59–5.54)% at one week after liver resection and 1.44 (0.70–3.50)% at one month after liver resection (p = 0.549). (b) Among 19 patients, 10 patients had MDSC >2% before liver resection. For these 10 patients, the frequency of MDSC was 7.75 ± 8.16% before operation, and decreased to 5.27 ± 6.37% at POW 1 and further to 1.51 ± 1.32% at POM 1 (p = 0.022).