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. 2019 Feb 19;9:2314. doi: 10.1038/s41598-018-38294-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Impaired retinal function in Dicer CKO. (A) Photopic waveforms of 4 month old control (black) and Dicer CKO (red) retinas at 72.25 cd.s/m². (B) Scotopic waveforms of 4 month old control (black) and Dicer CKO (red) retinas at 72.25 cd.s/m². (C,D) Light adapted photopic a- and b-wave amplitudes plotted at different light intensities for both control and Dicer CKO retinas. (E,F) Dark adapted scotopic a- and b-wave amplitudes plotted at different light intensities for both control and Dicer CKO retinas. (G) Scotopic 8 ms a-wave amplitudes for control and Dicer CKO retinas. (H) Fourrier analysis of photopic OPs at 72.25 cd.s/m². (I) Fourrier analysis of scotopic OPs at 72.25 cd.s/m². Cd: candela. OPs: Oscillatory potentials. Multiple T-test was performed. Sidak-Bonferroni was applied to correct for multiple testing. Adjusted p-value < 0.05 (*) was considered as significant. Error bars indicate standard error of the mean.