Fig. 1.

Comprehensive differentially expressed lncRNAs in cisplatin-resistant HepG2/CDDP cells. (a) The relative levels of 10 significantly deregulated lncRNAs were validated in HepG2/CDDP and HepG2 cells using real-time PCR, ^**p < 0.01, ^***p < 0.01. (b) qRT-PCR assays were used to detect NRAL expression levels in SMMC-7721/CDDP and HuH7/CDDP cells and their parental counterparts. β-Actin was used for normalization, *p < 0.05, **p < 0.01. (c) Genomic location of NRAL and the relationship with its target gene, NFE2L2(Nrf2)