Fig. 7.

(a, b) NRAL reverted the effects of miR-340-5p on HCC phenotypes resistant to cisplatin. mRNA (a, *p < 0.05, **p < 0.01) and protein (b) levels of Nrf2 in HepG and SMMC-7721 cells after co-transfection with ASO-miR-340-5p and pshR1+3-NRAL or in HepG2/CDDP and SMMC-7721/CDDP cells after co-transfection with pri-miR-340-5p and NRAL. β-actin was used as a reference gene, and the normalized values represent the means from at least 3 separate experiments, *p < 0.05 vs the NC group, ^&p < 0.05 vs the pcDNA group