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. 2018 Feb;154(3):624–636. doi: 10.1053/j.gastro.2017.10.005

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© 2018 The AGA Institute All rights reserved.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Summary of genes with putative regulatory functions in the developing ENS. (A) Transcription factors in the developing ENS. Left column includes genes with putative functions in stem cell maintenance versus neurogenesis. Right column includes genes with putative functions in specification and/or differentiation of enteric neurons. (B) Signaling factors in the developing ENS. Ligands expressed in the ENS (left column) or in proximal gut tissue (right column) presented with putative receptors. Ligand/receptor couples are likely involved in proliferation/differentiation or migration/network formation as indicated. See Supplementary Tables 6 and 7 for more information.