Table A1.

Assessment schedule

Assessment	Baseline	Week 2	Week 4	Week 8	Week 12	Ad hoc
Medical confirmation of eligibility, Structured Clinical Interview for DSM-5	✓	–	–	–	–	–
Randomisation	✓	–	–	–	–	–
Montgomery–Åsberg Depression Rating Scale	✓	✓	✓	✓	✓	–
24-item Hamilton Rating Scale for Depression	✓	✓	✓	✓	✓	–
Clinical Global Impression scale	✓	✓	✓	✓	✓	–
7-item Generalized Anxiety Disorder	✓	✓	✓	✓	✓	–
4-item modified Morisky Measurement of medication	✓	✓	✓	✓	✓	–
Simvastatin dispensed	✓	✓	✓	✓	✓	–
Treatment as usual/concomitant medication	✓	✓	✓	✓	✓	–
UKU adverse effects rating scale		✓	✓	✓	✓	✓
Basic clinical and psychiatric information	✓	–	–	–	–	–
Body mass index	✓	✓	–	✓	✓	–
Biomarkers (C-reactive protein, lipids)	✓	–	✓	–	✓	–
Telephone contact	–	–	–	–	–	✓