Table 2.

Mean (SD) change from baseline for Living with Pulmonary Hypertension questionnaire total scores (ITT analysis set).

Visit	n	Total score at visit (mean (SD))	Change from baseline (mean (SD))
Baseline*	75	46.03 (24.57)
Week 4	72	39.78 (22.72)	−7.65 (18.30)
Week 16	68	39.48 (22.57)	−6.98 (20.85)
Week 16 or Last Before†	75	39.83 (23.90)	−6.20 (21.43)
Week 24	66	37.17 (24.61)	−10.99 (22.51)
Last visit‡	75	40.63 (28.38)	−5.40 (27.8)

^*Last observed value before start of test drug.

^†Last observed value up to Visit 8 (week 16). If a patient died before week 16, the worst value of 105 was used.

^‡Last observed value (not including follow-up). If a patient died before week 24 or during follow-up after termination before week 24, the worst value of 105 was used.

ITT, intent to treat; SD, standard deviation.