Table 2.
Estimates for Changes in Behavioral Indices Over Time.
| Outcome Variable | Estimate | Standard Error | Degrees of Freedom | t | P |
|---|---|---|---|---|---|
| Carnitine levels | 0.548 | 0.191 | 10.3 | 2.86 | .016 |
| ABC Irritability | −0.088 | 0.066 | 7.9 | −1.32 | .223 |
| ABC Lethargy | −0.075 | 0.052 | 6.8 | −1.44 | .196 |
| ABC Stereotypy | −0.045 | 0.025 | 7.3 | −1.85 | .106 |
| ABC Hyperactivity | −0.155 | 0.060 | 8.9 | −2.58 | .030 |
| ABC Speech | −0.014 | 0.020 | 6.1 | −0.71 | .505 |
| ADOS SA | −0.008 | 0.017 | 8.6 | −0.45 | .663 |
| ADOS RRB | −0.001 | 0.011 | 8.3 | −0.13 | .897 |
| ADOS Total | −0.007 | 0.019 | 8.8 | −0.37 | .721 |
| SCQ Total | −0.071 | 0.028 | 6.2 | −2.55 | .043 |
| PDDBI Sensory | −0.068 | 0.047 | 8.9 | −1.46 | .179 |
| PDDBI Ritual | −0.015 | 0.087 | 8.1 | −0.18 | .863 |
| PDDBI SOCPP | −0.110 | 0.040 | 14 | −2.73 | .017 |
| PDDBI SEMPP | −0.085 | 0.063 | 7.4 | −1.36 | .212 |
| PDDBI Arouse | −0.132 | 0.067 | 8.9 | −1.97 | .081 |
| PDDBI Fears | −0.065 | 0.043 | 13 | −1.51 | .154 |
| PDDBI AGG | 0.007 | 0.115 | 8.2 | 0.06 | .956 |
| PDDBI REPRIT/C | −0.088 | 0.063 | 8.3 | −1.40 | .198 |
| PDDBI AWP/C | −0.099 | 0.070 | 8.5 | −1.41 | .193 |
| PDDBI SOCAPP | 0.108 | 0.027 | 5.4 | 3.96 | .009 |
| PDDBI Express | 0.010 | 0.023 | 8.6 | 0.41 | .693 |
| PDDBI LMRL | 0.006 | 0.034 | 4.5 | 0.18 | .862 |
| PDDBI EXSCA/C | 0.057 | 0.020 | 6.6 | 2.90 | .025 |
| PDDBI REXSCA/C | 0.054 | 0.022 | 7.7 | 2.42 | .043 |
| PDDBI Autism | −0.116 | 0.060 | 8.3 | −1.92 | .090 |
| AIM RRB-F | −0.034 | 0.076 | 4.5 | −0.44 | .681 |
| AIM RRB-I | −0.069 | 0.039 | 7 | −1.76 | .123 |
| AIM COMM-F | −0.022 | 0.021 | 13 | −1.08 | .301 |
| AIM COMM-I | −0.015 | 0.021 | 13 | −0.72 | .487 |
| AIM SER-F | −0.038 | 0.022 | 13.3 | −1.76 | .1013 |
| AIM SER-I | −0.060 | 0.026 | 13 | −2.31 | .038 |
| AIM OAB-F | −0.036 | 0.022 | 7.6 | −1.65 | .140 |
| AIM OAB-I | −0.031 | 0.020 | 8 | −1.57 | .156 |
Abbreviations: ABC, Aberrant Behavior Checklist; ADOS, Autism Diagnostic Observation Schedule; ADOS SA, ADOS Social Affect; ADOS RRB, ADOS Restricted and Repetitive Behavior; SCQ, Social Communication Questionnaire; PDDBI, Pervasive Developmental Disorder Behavior Inventory; PDDBI Sensory, PDDBI Sensory/Perceptual Approach Behaviors; PDDBI Ritual, PDDBI Ritualisms/Resistance to Change; PDDBI SOCPP, PDDBI Social Pragmatic Problems; PDDBI SEMPP, PDDBI Semantic/Pragmatic Problems; PDDBI Arouse, PDDBI Arousal Regulation Problems; PDDBI Fears, PDDBI Specific Fears; PDDBI AGG, PDDBI Aggressiveness; PDDBI REPRIT/C, PDDBI Repetitive, Ritualistic, and Pragmatic Problems Composite; PDDBI AWP/C, PDDBI Approach/Withdrawal Problems Composite; PDDBI SOCAPP, PDDBI Social Approach Behaviors; PDDBI Express, PDDBI Expressive Language; PDDBI LMRL, PDDBI Learning, Memory, and Receptive Language; PDDBI EXSCA/C, PDDBI Expressive Social Communication Abilities Composite; PDDBI REXSCA/C, PDDBI Receptive/Expressive Social Communication Abilities Composite; PDDBI Autism, PDDBI Autism Composite; AIM, Autism Impact Measure; AIM RRB-F, AIM Restricted/Repetitive Behavior Frequency; AIM RRB-I = AIM Restricted/Repetitive Behavior Impact; AIM COMM-F, AIM Communication/Language Frequency; AIM COMM-I, AIM Communication/Language Impact; AIM SER-F, AIM Social-Emotional Reciprocity Frequency; AIM SER-I, AIM Social-Emotional Reciprocity Impact; AIM OAB-F, AIM Odd/Atypical Behavior Frequency; AIM OAB-I, AIM Odd/Atypical Behavior Impact. P-values in bold reflect those that are significant at less than .05.