Table 5.
Multivariable analyses of risk of death in veterans with PH.
| Risk of death |
|||
|---|---|---|---|
| Covariate | HR | 95% CI | P-value |
| Effect of PH Group, adjusted for age at PH diagnosis, gender, race | |||
| Age at PH Dx (each 10 y) | 1.46 | 1.45, 1.47 | <.0001 |
| Sex (M vs. F) | 1.36 | 1.30, 1.43 | <.0001 |
| White race | Ref | ||
| Black race | 1.05 | 1.02, 1.07 | <.0001 |
| Other race | 0.98 | 0.93, 1.04 | 0.48 |
| PH Group | |||
| Group 1 PAH | Ref | ||
| Group 2 PH-LHD | 1.97 | 1.89, 2.04 | <.0001 |
| Group 3 PH, lung disease | 1.58 | 1.52, 1.65 | <.0001 |
| Group 4 CTEPH | 0.88 | 0.79, 0.97 | 0.01 |
| Group 5 miscellaneous PH | 1.06 | 0.88, 1.27 | 0.53 |
| PH with multiple causes | 2.54 | 2.45, 2.63 | <.0001 |
| Effect of comorbidity, adjusted for age at PH diagnosis, gender, race | |||
| Age at PH Dx (each 10 y) | 1.42 | 1.41, 1.44 | <.0001 |
| Sex (M vs. F) | 1.31 | 1.25, 1.38 | <.0001 |
| White race | Ref | ||
| Black race | 0.92 | 0.90, 0.94 | <.0001 |
| Other race | 0.91 | 0.86, 0.96 | 0.0012 |
| Elixhauser condition | |||
| Congestive Heart Failure | 1.59 | 1.56, 1.62 | <.0001 |
| Cardiac Arrhythmia | 0.98 | 0.97, 1.00 | 0.08 |
| Valvular Disease | 0.91 | 0.89, 0.92 | <.0001 |
| Peripheral Vascular Disease | 1.11 | 1.09, 1.13 | <.0001 |
| Hypertension, Uncomplicated | 0.79 | 0.76, 0.81 | <.0001 |
| Hypertension, Complicated | 1.01 | 0.99, 1.03 | 0.52 |
| Paralysis | 1.07 | 1.03, 1.11 | 0.0009 |
| Other Neurological Disorders | 1.10 | 1.07, 1.13 | <.0001 |
| Chronic Pulmonary Disease | 1.40 | 1.34, 1.47 | <.0001 |
| Diabetes, Uncomplicated | 1.06 | 1.04, 1.08 | <.0001 |
| Diabetes, Complicated | 1.10 | 1.07, 1.12 | <.0001 |
| Hypothyroidism | 1.00 | 0.98, 1.02 | 0.99 |
| Renal Failure | 1.23 | 1.20, 1.26 | <.0001 |
| Liver Disease | 1.21 | 1.19, 1.24 | <.0001 |
| Peptic Ulcer Disease | 0.98 | 0.95, 1.01 | 0.15 |
| AIDS/HIV | 0.98 | 0.89, 1.08 | 0.71 |
| Lymphoma | 1.21 | 1.16, 1.27 | <.0001 |
| Cancer, Metastatic | 1.81 | 1.74, 1.87 | <.0001 |
| Solid Tumor, Without Metastasis | 1.09 | 1.07, 1.11 | <.0001 |
| Collagen Vascular Disease | 0.97 | 0.95, 0.98 | 0.0001 |
| Coagulopathy | 1.15 | 1.13, 1.17 | <.0001 |
| Obesity | 0.79 | 0.78, 0.80 | <.0001 |
| Weight Loss | 1.32 | 1.30, 1.35 | <.0001 |
| Fluid and Electrolyte Disorders | 1.36 | 1.34, 1.38 | <.0001 |
| Blood Loss Anemia | 1.10 | 1.06, 1.14 | <.0001 |
| Deficiency Anemia | 1.08 | 1.06, 1.10 | <.0001 |
| Alcohol Abuse | 1.15 | 1.12, 1.17 | <.0001 |
| Drug Abuse | 1.03 | 1.00, 1.05 | 0.06 |
| Psychoses | 1.17 | 1.14, 1.19 | <.0001 |
| Depression | 1.01 | 0.99, 1.03 | 0.40 |
Abbreviations same as in Table 4.