Table 2.
Bronchoalveolar pH and other variables in bronchoalveolar fluid and serum in patients with AECOPD versus those with stable COPD.
| Bacteria isolated in AECOPD |
Stable COPD controls (n = 42) | ||
|---|---|---|---|
| No (n = 24) | Yes (n = 60) | ||
| Lung pH | 6.31 ± 0.55 | 7.13 ± 0.52* | 6.21 ± 0.37‡ |
| BA-LDH (U/L) | 361 ± 250 | 1381 ± 1621* | 124 ± 50†,‡ |
| S-LDH (U/L) | 173 ± 36 | 188 ± 24* | 160 ± 25‡ |
| BA-CRP (mg/L) | 0.17 ± 0.34 | 0.14 ± 0.26 | 0.12 ± 0.11 |
| S-CRP (mg/L) | 16.8 ± 11.6 | 29.4 ± 11.2* | 4.3 ± 2.6†,‡ |
| BA-Glu (mmol/L) | 1.6 ± 0.7 | 0.9 ± 0.7* | 1.6 ± 0.6‡ |
| S-Glu (mmol/L) | 5.8 ± 0.7 | 6.1 ± 1.4 | 5.6 ± 1.2‡ |
Data are presented as mean ± standard deviation. AECOPD, acute exacerbation of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease; BA-LDH, bronchoalveolar lactate dehydrogenase; S-LDH, serum lactate dehydrogenase; BA-CRP, bronchoalveolar C-reactive protein; S-CRP, serum C-reactive protein; BA-Glu, bronchoalveolar glucose; S-Glu, serum glucose. *p < 0.05, non-isolated bacteria versus isolated bacteria; †p < 0.05, non-isolated bacteria versus stable COPD controls; ‡p < 0.05, isolated bacteria versus stable COPD controls.