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. 2018 Nov 12;47(2):689–701. doi: 10.1177/0300060518808162

Table 4.

Predictors of cognitive dysfunction at 5 and 7 days postoperatively.


Univariate analysis
Multivariate logistic regression analysis 5 days postoperatively
Multivariate logistic regression analysis7 days postoperatively
Predictors P value OR (95% CI) P value OR (95% CI) P value
Smoking history 0.009 0.833 (0.497‒0.911) 0.006 0.684 (0.583‒0.952) 0.002
Dose of sufentanil 0.026 2.901 (2.127‒16.381) 0.007 1.073 (1.005‒1.632) 0.036
Age 0.001 1.922 (1.057‒2.132) 0.018 2.890 (1.583‒9.581) 0.023
Lower education level 0.039 2.512 (1.603‒15.244) 0.034 3.800 (1.200‒13.493) 0.040
Serum TNF-α concentration 0.001 2.903 (1.572–4.484) 0.042 1.437 (1.206–1.680) 0.027
Anesthesia duration 0.001 1.783 (1.514‒7.366) 0.047
History of general anesthesia 0.001 3.674 (2.496‒4.217) 0.044
History of allergy 0.001
Blood transfusion 0.001

OR, odds ratio; CI, confidence interval; TNF-α, tumor necrosis factor-α.