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. 2018 Sep 14;112(6):294–305. doi: 10.1080/20477724.2018.1514136

Figure 3.

Figure 3.

TDV vaccine candidate.

The Takeda tetravalent vaccine TDV has been generated by substituting prM and E genes from DENV-1, DEN-3, and DENV-4 into TDV-2 backbone. TDV2 is an over-attenuated mutant of DENV-2 vaccine candidate DENV-2-PDK53.