Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LAV Delta 30 vaccine candidate.
The tetravalent dengue vaccine LAV Delta 30 (or TV003) is composed of four mutants DENV-1 to DEN-4 which contain a deletion of 30 nucleotides (∆30) in the domain II of the 3ʹNTR of their genomic RNA. mutant DENV-4 virus ∆30 was used as a backbone to generate a chimeric DENV-2 virus ∆30 by substitution of the prM and E genes.
