Table 3.
Sociodemographic and Clinical Characteristics Associated With Statin Use in US Adults With Severe Dyslipidemia (Adjusted LDL-C ≥190 mg/dL)
| Unadjusted | Multivariable Adjusted | |||
|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | |
| Age, y | ||||
| 20–39 | 1.0 | — | 1.0 | — |
| 40–59 | 3.5 (2.4–5.1) | <0.001 | 2.5 (1.7–3.7) | <0.001 |
| ≥60 | 6.7 (4.7–9.6) | <0.001 | 3.7 (2.6–5.5) | <0.001 |
| Female sex | 1.4 (1.1–1.6) | 0.002 | — | — |
| Race | — | — | ||
| Non-Hispanic white | 1.0 | — | ||
| Non-Hispanic black | 1.1 (0.9–1.3) | 0.56 | ||
| Mexican American | 0.6 (0.5–0.8) | <0.001 | ||
| Other | 0.7 (0.5–1.0) | 0.08 | ||
| Education | — | — | ||
| Less than high school | 1.0 | — | ||
| High school graduate | 1.1 (0.9–1.4) | 0.41 | ||
| Some college or more | 1.1 (0.9–1.4) | 0.27 | ||
| Insurance status | ||||
| Uninsured | 1.0 | — | 1.0 | — |
| Intermittently insured | 2.0 (1.1–3.5) | 0.025 | 1.6 (0.8–2.9) | 0.16 |
| Fully insured | 3.9 (2.6–5.8) | <0.001 | 2.3 (1.5–3.6) | <0.001 |
| Poverty (<133% poverty line) | 0.8 (0.6–0.9) | 0.006 | — | — |
| US-born | 0.8 (0.6–1.0) | 0.017 | — | — |
| Usual source of care | ||||
| None | 1.0 | — | 1.0 | — |
| Hospital outpatient or emergency | 5.7 (3.5–9.4) | <0.001 | 3.6 (2.2–6.0) | <0.001 |
| Doctor’s office or clinic | 6.7 (4.1–10.9) | <0.001 | 3.8 (2.3–6.2) | <0.001 |
| Body mass index | — | — | ||
| Normal weight (≤24.9 kg/m2) | 1.0 | — | ||
| Overweight (25–29.9 kg/m2) | 0.9 (0.7–1.2) | 0.59 | ||
| Obese (≥30 kg/m2) | 1.1 (0.8–1.4) | 0.75 | ||
| Smoking status | — | — | ||
| Never | 1.0 | — | ||
| Past | 1.3 (1.0–1.6) | 0.06 | ||
| Current | 0.7 (0.5–0.9) | 0.008 | ||
| Glucose tolerance | ||||
| Normal | 1.0 | — | 1.0 | — |
| Prediabetic | 1.4 (1.1–1.7) | 0.005 | 1.2 (0.9–1.5) | 0.24 |
| Diabetic | 1.9 (1.5–2.4) | <0.001 | 1.4 (1.1–1.8) | 0.005 |
| Blood pressure | — | |||
| Normal | 1.0 | — | 1.0 | |
| Prehypertensive | 1.1 (0.8–1.4) | 0.72 | 0.9 (0.7–1.3) | 0.69 |
| Hypertensive | 2.2 (1.7–2.8) | <0.001 | 1.4 (1.0–1.9) | 0.036 |
| Personal history of early ASCVD | 2.5 (1.7–3.6) | <0.001 | 2.0 (1.3–2.9) | 0.001 |
| Family history of early ASCVD | 1.2 (0.9–1.5) | 0.28 | — | — |
ASCVD indicates atherosclerotic cardiovascular disease; CI, confidence interval; LDL-C, low-density lipoprotein cholesterol; and OR, odds ratio.