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. 2019 Feb 20;14:59. doi: 10.1186/s13018-019-1091-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Identification of H4 acetylation after stimulation by IL-1β or TNF-α. a–c SW1353 cells were stimulated with or without IL-1β (10 ng/ml) or TNF-α (10 ng/ml) for 6 h and analyzed by ChIP for H4K5Ac, H4K8Ac, and H4K12Ac. The quantitative analysis of targeted promoter regions was determined by real-time PCR using specific primers for MMP1, MMP3, MMP13, and ADAMTS4. Relative fold-change values were calculated in comparison with the vehicle control that was set to 1 (n = 2)