Table 5.
Percent antibiotic susceptibility of gram-positive bacteria (S. aureus, S. pneumoniae, Enterococcus spp.) during 2015/2016 compared to corresponding susceptibility results in 2011/2013a
| Antibiotic | S. aureus | S. pneumoniae | Enterococcus spp. | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011/2013 N (%S) | 2015/2016 N (%S) | OR (95% CI) | P | 2011/2013 N (%S) | 2015/2016 N (%S) | OR (95% CI) | P | 2011/2013 N (%S) | 2015/2016 N (%S) | OR (95% CI) | P | |
| Ampicillin | NA | NA | NA | NA | NA | NA | NA | NA | 3847 (84%) | 3760 (75%) | 0.57 (0.51–0.64) | 0.0001 |
| Clindamycin | 4359 (83%) | 6452 (81%) | 0.87 (0.79–0.96) | 0.01 | 588 (76%) | 584 (75%) | 0.95 (0.73–1.24) | 1 | NA | NA | NA | NA |
| Erythromycin | 4890 (76%) | 6304 (73%) | 0.85 (0.78–0.93) | 0.0004 | 544 (63%) | 584 (65%) | 1.09 (0.86–1.39) | 1 | NA | NA | NA | NA |
| Levofloxacin | 2297 (84%) | 2873 (72%) | 0.49 (0.43–0.56) | 0.0001 | 483 (91%) | 584 (99%) | 1.07 (0.72–1.40) | 1 | NA | NA | NA | NA |
| Oxacillin | 4752 (73%) | 6452 (72%) | 0.95 (0.87–1.03) | 0.25 | NA | NA | NA | NA | NA | NA | NA | NA |
| Tigecycline | 492 (99%) | 1788 (99%) | 1.03 (0.33–2.63) | 0.985 | NA | NA | NA | NA | 723 (99%) | 1022 (99%) | 0.10 (0.35–1.64) | 0.983 |
| Trimethoprim/sulfamethoxazole | 4604 (91%) | 6437 (88%) | 0.73 (0.64–0.82) | 0.0001 | 296 (53%) | 398 (55%) | 1.08 (0.80–1.47) | 1 | NA | NA | NA | NA |
| Vancomycin | 4890 (100%) | 6452 (100%) | 1.32 (0.03–1.47) | 0.819 | NA | NA | NA | NA | 4145 (99%) | 3760 (98%) | 0.49 (0.33–0.72) | 0.0003 |
KEY = CI confidence interval, N Number of isolates tested in each bacteria/antibiotic combination, NA not available, OR Odds Ratio, S Susceptibility, % percent
P < 0.05 is considered statistically significant
aThe 2011/2013 data are taken from: Chamoun K, Farah M, Araj G, et al. Surveillance of antimicrobial resistance in Lebanese hospitals: retrospective nationwide compiled data. Int J Infect Dis. 2016;46:64–70