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. 2019 Feb 20;17:14. doi: 10.1186/s12964-019-0326-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Glucose-dependent regulated phosphoproteins and phosphorylated sites (p-sites) overtime. a Table (*successfully quantified at least twice in all experimental conditions; **p-value < 0.05 and FC (Log2) > 0.3 or < − 0.3). b Volcano plots displaying the distribution of significant regulated p-sites overtime. P-sites significantly changed (p-value < 0.05) and FC (Log2) > 0.3 or < − 0.3 compared to control are shown in color. c Heat maps, showing enrichment of cell process related with insulin secretion, and cell localization / organelle enrichment. d Venn diagrams showing numbers and percentages of common and differentially regulated p-sites overtime