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. 2019 Feb 20;17:14. doi: 10.1186/s12964-019-0326-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of modulators of KSEA-identified kinases on glucose-stimulated mitochondrial respiration. a Normalized effect of drugs tested on glucose-stimulated mitochondrial respiration, including p-values. In the inset, oxygen consumption recording in INS-1E cells. Protocol designed to identify the effect of glucose-regulated kinases on glucose-driven mitochondrial respiration. From b to g) Effect of AICAR, PD98059, KT5720, Wortmanin, Go-6983 and KN62, on glucose-stimulated mitochondrial respiration