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. 2018 Dec 24;115(51-52):855–862. doi: 10.3238/arztebl.2018.0855

Table 1. Characteristics and functional outcomes of studies included in review (surgery/conservative treatment).

First
author, year (reference),
design
1. n
(surgery/conservative
treatment)
2. Age (surgery/
conservative treatment)
3. Follow-up, months
Anteroposterior stability
(side-to-side difference [mm])
(surgery/conservative treatment)
Lysholm score
(surgery/conservative
treatment)
Mean IKDC score:
1. Normal
2. Almost normal
3. Abnormal
4. Very abnormal
(surgery/conservative treatment)
KOOS score (surgery/
conservative treatment):
1. Symptoms
2. Pain
3. ADL
4. Sport
5. QOL
Seitz
1994 (4)
RCS
1. 63 / 24
2. Surgery: 27 (15 to 42)
Conservative: 28 (18 to 56)
3. 102 (60 to 144)
<3 mm category:
86% / 8%
100 to 91 (49 / 12)
90 to 84 (14 / –)
83 to 65 (– / 6)
64 to 0 (– / 6)
Wittenberg
1998 (7)
RCS
1. 30 / 30
2. 34.3 (22 to 50)
3. 39 (24 to 36)
2 / 4*1 86 / 72*1
Fink
2001 (29)
RCS
1. 72 / 41
2. 33.0 (± 9.0)
3. Surgery: 132.1 (± 8.1)
Conservative: 140.0
(± 9.6)
2.0 (± 1.5) / 4.0 (± 2.0)*1 96 / 83*1 1.    0% /    0% *1
2. 44% /    4%
3. 52% / 52%
4.    4% / 44%
Fithian
2005 (22)
PCS
1. 63 (early surgery) /
33 (delayed surgery) /
113 (conservative)
2. 39.0 (16–69)
3. 79
High risk: 1.6 (± 1.6) / 3.3 (± 1.5)
Moderate risk : 1.7 (± 2.0) / 3.1 (± 2.0)
Low risk : 2.0 (± 2.0) /
2.3 (±1.8)* 1
92 (± 10)/
88 (± 14)*1. 2
1. 33% / 10% *1. 2
2. 50% / 23%
3. 16% / 66%
4.    1% /    2%
Kessler
2008 (27)
RCS
1. 60 / 49
2. 30.7 (12.5 to 54.0)
3. 132
3.9 (0 to 12) / 5.7 (0 to 16)*1 1. 53% / 14% *1
2. 18% / 41%
3. 20% / 31%
4. 8% / 14%
Tsoukas
2016 (21)
RCT
1. 17 / 15
2. Surgery: 31 (20 to 36)
Conservative: 33
(25 to 39)
3. 123
1.5 (± 0.2) / 4.5 (± 0.5)*1 1. 86.8 (± 6.5)/
77.5 (± 13)*1
Streich
2011 (28)
RCS
1. 40 / 40
2. 25.8 (17 to 39)
3. 180 (± 17)
2.0 / 2.1 68.0 (± 19.8)/
75.5 (± 15.9)
1. 69.9 (± 17.0)/
75.9 (± 13.1)
Grindem
2012 (25)
PCS
1. 69 / 69
2. 27.6 (13 to 60)
3. 12.8 (± 1.2)
2.7 (± 1.8)/5.6 (± 2.8)*1 1. 85.0 (± 11.6)/
88.5 (± 9.2)
Markström
2018 (26)
PCS
1. 327/ 34
2. Surgery: 46 (± 4.6)
Conservative: 48 (± 5.9)
3. 276
2.0 (± 2.7) / 4.9 (± 2.9) 81 (± 64)/
73 (± 61)
1. 84 / 75
2. 82 / 89
3. 89 / 98*1
4. 50 / 75*1
5. 49 / 69*1
Meuffels
2009 (3).
van Yperen
2018 (6)
RCS
1. 25 / 25
2. 37.7 (± 6.5)
3. 272
>3 mm category (2009):
6 (24%) / 17 (68%)*1

3 mm category (2018):
10 (40%) / 19 (83%)*1
2009:
88.0 (80.5 to 91.0)/
85.0 (77.0 to 90.0)

2018:
86.0 (75.5 to 91.0)/
89.0 (75.5 to 95.5)
2009:
1. 77.1 (65.1 to 87.3)/
77.1 (67.5 to 84.9) 2018:

1. 81.6 (59.8 to 89.1)/
78.2 (61.5 to 92.0)
2018:
1. 86 / 93
2. 92 / 97
3. 96 / 99
4. 85 / 85
5. 63 / 69
Myklebust
2003 (23)
PCS
1. 57 / 22
2. Not stated
3. 94
>3 mm category:
40% / 41%
85 (± 13)/
85 (± 13)*2
1.    9% /4%
2. 31% /13%
3. 23% /7%
4. 13% /0%
Moksnes
2009 (24)
PCS
1. 52 / 50
2. 27.2 (± 8.6)
3. 12
4.1 (± 0.7) / 7.6 (± 0.5)*1 1. 87.0 (± 1.7)/
86.1 (± 1.6)
Frobell
2013 (14)
RCT
1. 62*3 / 59
2. 26.5 (± 5.0)
3. 62
6.6 / 8.3*1 1. 83 (78 to 87) / 87 (79 to 95)*3
2. 91 (88 to 94) / 91 (86 to 96)
3. 95 (93 to 97) / 97 (93 to 100)
4. 76 (70 to 81) / 79 (68 to 90)
5. 71 (65 to 76) / 69 (58 to 80)

*1p <0.05; *2 copers; *3 including delayed anterior cruciate ligament reconstruction

ADL: activities of daily living; IKDC: International Knee Documentation Committee; KOOS: Knee Injury and Osteoarthritis Outcome Score; QOL: quality of life; PCS: prospective cohort study;

RCT: randomized controlled trial; RCS: retrospective cohort study