eTable 2c. Characteristics and functional outcomes of studies included in review that found no significant difference in knee function between conservative treatment and surgery, with suboptimum knee-joint stability.
First author, year (reference) (design) |
n (surgery/ conservative treatment) |
Time to surgery (months) |
Age (years) |
Follow-up (months) |
Anteroposterior stability (side-to-side difference [mm]) (surgery/conservative treatment) | Clinical stability, pivot shift, Lachman (surgery/conservative treatment) (clinical [%]) |
Crossover rate (%) |
Lysholm (surgery/ conservative treatment) |
Tegner (surgery/ conservative treatment) |
IKDC (surgery/ conservative treatment) |
KOOS (surgery/ conservative treatment) |
Single-leg hop test (surgery/ conservative treatment) |
RTS/RTPL (surgery/ conservative treatment) (%) |
Myklebust 2003 (23) (PCS) |
57 / 22 | Not stated | Not stated | 94 | <3 mm category: 40% / 41% |
– | – | 85 (± 13) / 85 (± 13)*1 |
– | Normal: 9% / 4% Almost normal: 31% / 13% Abnormal: 23% / 7% Very abnormal: 13% / 0% |
– | 7 (± 3) / 2 (± 3) (difference in hop between injured & uninjured legs, cm) |
58 / 82 |
Moksnes 2009 (24) (PCS) |
52 / 50 | 6 (after 3 months’ rehab) |
27.2 (± 8.6) |
12 | 4.1 (± 0.7) / 7.6 (± 0.5)*2 |
– | 16.1 (10 / 62) |
– | – | 87.0 (± 1.7) / 86.1 (± 1.6) |
– | 91.8 (± 1.4) / 95.9 (± 1.4)*2 (hop, % vs. uninjured leg) |
– |
Frobell 2013 (14) (RCT) |
62*3 / 59 | <2.5 | 26.5 (± 5.0) |
62 | 6.6 / 8.3*2 | 76 / 40 (pivot) 76 / 32 (Lachman) |
51 (30 / 59) |
– | 4 (2 to 7) / 4 (2 to 6.5) |
– | Symptoms: 83 (78 to 87)/ 87 (79 to 95) Pain: 91 (88 to 94) / 91 (86 to 96) ADL: 95 (93 to 97) / 97 (93 to 100) Sport: 76 (70 to 81) / 79 (68 to 90) QOL: 71 (65 to 76)/ 69 (58 to 80) |
– | – |
Meuffels 2009 (3)/ van Yperen 2018 (6) (RCS) |
25 / 25 | 6 (2 to 258) | 37.7 (± 6.5) |
272 | >3 mm category (2009): 6 (24%) / 17 (68%)*2 (2018): 10 (40%) / 19 (83%)*2 |
2009: 20 / 84 (≥1 + pivot) 2018: 32 / 87 (≥1 + pivot) |
– | 2009: 88.0 (80.5 to 91.0)/ 85.0 (77.0 to 90.0) 2018: 86.0 (75.5 to 91.0) / 89.0 (75.5 to 95.5) |
2009: 6 (4 to 7) / 5 (4 to 7) 2018: 5 (3 to 6) / 4 (4 to 6) |
2009: 77.1 (65.1 to 87.3) / 77.1 (67.5 to 84.9) 2018: 81.6 (59.8 to 89.1) / 78.2 (61.5 to 92.0) |
2018: Symptoms: 86 / 93 Pain: 92 / 97 ADL: 96 / 99 Sport: 85 / 85 QOL: 63 / 69 |
2009: 93.7 (80.0 to 100.7)/ 96.1 (84.2 to 100.9) 2018: 85.9 (68.1 to 101.9) / 95.1 (70.8 to 104.7) (hop, % vs. uninjured leg) |
– |
ADL: activities of daily living; IKDC: International Knee Documentation Committee; KOOS: Knee Injury and Osteoarthritis Outcome Score; PCS: prospective cohort study; QOL: quality of life; RCT: randomized controlled trial; RCS: retrospective cohort study;
RTS: rate of return to sport; RTPL: rate of return to preinjury level; *1 copers; *2 p <0.05; *3 including delayed anterior cruciate ligament reconstruction