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. 2019 Feb 19;19:177. doi: 10.1186/s12879-019-3792-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Maximum likelihood phylogenies of recombinant GII.4 strains that emerged in Alberta. Three different GII.4 Sydney recombinant strains were identified based on sequences of (a) the 3’end of ORF1 and (b) region C of the capsid gene. The novel GII.P16/GII.4 Sydney strains are shown with solid circles; GII.P4 New Orleans/GII.4 Sydney and GII.Pe/GII.4 Sydney strains are shown with solid squares and solid triangles, respectively. Trees A and B were constructed using the Kimura-2 parameter substitution model assuming gamma-distributed rates of evolution among sites with (tree A) and without (tree B) invariant sites. Branch significance was estimated based on 1000 bootstrap replicates