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. 2019 Jan 9;127(1):017002. doi: 10.1289/EHP3523

Table 2.

Urinary phenols and phthalate metabolite concentrations among mother–son pairs of the EDEN (Etude des Déterminants pré et postnatals du développement et de la santé de l’Enfant) cohort with (N=473) and without (N=131) placental weight information.

Analyte LOD (μg/L) % >LOD Study population Percentiles (μg/La) Mothers of the EDEN cohort with biomarker concentrations but missing placental weight Percentiles (μg/La) p-Valuesb
n 5th 50th 95th n 5th 50th 95th
Phenols                      
 2,4-DCP 0.2 98 473 0.23 0.95 9.00 131 0.35 1.01 8.39 0.20
 2,5-DCP 0.2 100 473 1.67 9.04 279 131 2.84 11.8 227 0.09
DCP (μmol/L) 473 0.01 0.06 1.78 131 0.02 0.08 1.44 0.08
 BPA 0.4 99 473 0.83 2.34 9.76 131 0.86 2.37 7.86 0.53
 BP3 0.4 92 473 0.22 2.23 79.4 131 0.12 2.32 69.1 0.94
 TCS 2.3 79 473 0.15 25.5 686 131 1.27 30.9 750 0.03
 MP 1 100 473 7.52 100 1232 131 9.39 150 1515 0.04
 EP 1 71 473 0.08 3.11 65.4 131 0.08 4.69 68.7 0.02
 PP 0.2 99 473 0.40 12.0 263 131 0.84 18.5 226 0.02
 BP 0.2 85 473 0.09 1.63 57.6 131 0.09 2.13 57.6 0.34
PB (μmol/L) 473 0.06 0.82 10.2 131 0.06 1.41 11.8 0.04
Phthalates                      
 MEP 0.6 100 473 21.2 94.0 713 131 28.8 133 968 0.04
 MBP 0.2 100 473 11.7 43.4 454 131 15.5 49.7 423 0.07
 MiBP 0.2 100 473 11.8 39.4 170 131 15.1 48.9 175 0.01
 MBzP 0.3 100 473 4.47 18.2 100 131 5.25 19.3 114 0.30
 MCPP 0.2 100 473 0.68 1.97 10.0 131 0.72 1.91 9.14 0.68
 MEHP 0.5 98 473 1.30 7.40 33.7 131 1.44 7.69 38.1 0.48
 MEHHP 0.2 100 473 6.41 27.7 98.5 131 7.25 25.6 116 0.95
 MEOHP 0.2 100 473 5.28 22.9 81.6 131 6.39 21.2 90.6 0.68
 MECPP 0.2 100 473 12.0 38.9 156 131 13.1 37.9 169 0.64
DEHP (μmol/L) 473 0.09 0.33 1.19 131 0.10 0.31 1.37 0.70
 MCOP 0.2 100 473 1.17 3.86 17.4 131 1.31 4.21 20.3 0.18
 MCNP 0.2 99 473 0.49 1.26 10.2 131 0.56 1.34 10.9 0.69

Note: —, not applicable; LOD, Limit of detection; 2,4-DCP, 2,4-dichlorophenol; 2,5-DCP, 5-dichlorophenol; BP, butyl paraben; BP3, benzophenone 3; BPA, bisphenol A; EP, ethyl paraben; MBP, mono-n-butyl phthalate; MBzP, monobenzyl phthalate; MCNP, monocarboxyisononyl phthalate; MCOP, monocarboxy-isooctyl phthalate; MCPP, mono(3-carboxypropyl) phthalate; MECPP, mono(2-ethyl-5-carboxypentyl) phthalate; MEHHP; MEHHP, mono(2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono(2-ethylhexyl) phthalate; MEOHP and MECPP; MEOHP, mono(2-ethyl-5-oxohexyl) phthalate; MEP, monoethyl phthalate; MiBP, mono-isobutyl phthalate; MP, methyl paraben; PP, propyl paraben; TCS, triclosan; DCP, molar sum of dichlorophenols; DEHP, molar sum of MEHP; PB, molar sum of parabens (methyl-, ethyl-, propyl- and butylparaben).

a

Concentrations are given in μg/L for all compounds but the sums of dichlorophenols, of parabens, and of DEHP metabolites.

b

p-Values for the Wilcoxon rank-sum test.