Table 2.
Analyte | LOD () | % | Study population Percentiles (a) | Mothers of the EDEN cohort with biomarker concentrations but missing placental weight Percentiles (a) | p-Valuesb | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
5th | 50th | 95th | 5th | 50th | 95th | ||||||
Phenols | |||||||||||
2,4-DCP | 0.2 | 98 | 473 | 0.23 | 0.95 | 9.00 | 131 | 0.35 | 1.01 | 8.39 | 0.20 |
2,5-DCP | 0.2 | 100 | 473 | 1.67 | 9.04 | 279 | 131 | 2.84 | 11.8 | 227 | 0.09 |
() | — | — | 473 | 0.01 | 0.06 | 1.78 | 131 | 0.02 | 0.08 | 1.44 | 0.08 |
BPA | 0.4 | 99 | 473 | 0.83 | 2.34 | 9.76 | 131 | 0.86 | 2.37 | 7.86 | 0.53 |
BP3 | 0.4 | 92 | 473 | 0.22 | 2.23 | 79.4 | 131 | 0.12 | 2.32 | 69.1 | 0.94 |
TCS | 2.3 | 79 | 473 | 0.15 | 25.5 | 686 | 131 | 1.27 | 30.9 | 750 | 0.03 |
MP | 1 | 100 | 473 | 7.52 | 100 | 1232 | 131 | 9.39 | 150 | 1515 | 0.04 |
EP | 1 | 71 | 473 | 0.08 | 3.11 | 65.4 | 131 | 0.08 | 4.69 | 68.7 | 0.02 |
PP | 0.2 | 99 | 473 | 0.40 | 12.0 | 263 | 131 | 0.84 | 18.5 | 226 | 0.02 |
BP | 0.2 | 85 | 473 | 0.09 | 1.63 | 57.6 | 131 | 0.09 | 2.13 | 57.6 | 0.34 |
() | — | — | 473 | 0.06 | 0.82 | 10.2 | 131 | 0.06 | 1.41 | 11.8 | 0.04 |
Phthalates | |||||||||||
MEP | 0.6 | 100 | 473 | 21.2 | 94.0 | 713 | 131 | 28.8 | 133 | 968 | 0.04 |
MBP | 0.2 | 100 | 473 | 11.7 | 43.4 | 454 | 131 | 15.5 | 49.7 | 423 | 0.07 |
MiBP | 0.2 | 100 | 473 | 11.8 | 39.4 | 170 | 131 | 15.1 | 48.9 | 175 | 0.01 |
MBzP | 0.3 | 100 | 473 | 4.47 | 18.2 | 100 | 131 | 5.25 | 19.3 | 114 | 0.30 |
MCPP | 0.2 | 100 | 473 | 0.68 | 1.97 | 10.0 | 131 | 0.72 | 1.91 | 9.14 | 0.68 |
MEHP | 0.5 | 98 | 473 | 1.30 | 7.40 | 33.7 | 131 | 1.44 | 7.69 | 38.1 | 0.48 |
MEHHP | 0.2 | 100 | 473 | 6.41 | 27.7 | 98.5 | 131 | 7.25 | 25.6 | 116 | 0.95 |
MEOHP | 0.2 | 100 | 473 | 5.28 | 22.9 | 81.6 | 131 | 6.39 | 21.2 | 90.6 | 0.68 |
MECPP | 0.2 | 100 | 473 | 12.0 | 38.9 | 156 | 131 | 13.1 | 37.9 | 169 | 0.64 |
() | — | — | 473 | 0.09 | 0.33 | 1.19 | 131 | 0.10 | 0.31 | 1.37 | 0.70 |
MCOP | 0.2 | 100 | 473 | 1.17 | 3.86 | 17.4 | 131 | 1.31 | 4.21 | 20.3 | 0.18 |
MCNP | 0.2 | 99 | 473 | 0.49 | 1.26 | 10.2 | 131 | 0.56 | 1.34 | 10.9 | 0.69 |
Note: —, not applicable; LOD, Limit of detection; 2,4-DCP, 2,4-dichlorophenol; 2,5-DCP, 5-dichlorophenol; BP, butyl paraben; BP3, benzophenone 3; BPA, bisphenol A; EP, ethyl paraben; MBP, mono-n-butyl phthalate; MBzP, monobenzyl phthalate; MCNP, monocarboxyisononyl phthalate; MCOP, monocarboxy-isooctyl phthalate; MCPP, mono(3-carboxypropyl) phthalate; MECPP, mono(2-ethyl-5-carboxypentyl) phthalate; MEHHP; MEHHP, mono(2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono(2-ethylhexyl) phthalate; MEOHP and MECPP; MEOHP, mono(2-ethyl-5-oxohexyl) phthalate; MEP, monoethyl phthalate; MiBP, mono-isobutyl phthalate; MP, methyl paraben; PP, propyl paraben; TCS, triclosan; , molar sum of dichlorophenols; , molar sum of MEHP; , molar sum of parabens (methyl-, ethyl-, propyl- and butylparaben).
Concentrations are given in for all compounds but the sums of dichlorophenols, of parabens, and of DEHP metabolites.
p-Values for the Wilcoxon rank-sum test.