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. 2006 Jan 4;26(1):41–50. doi: 10.1523/JNEUROSCI.4308-05.2006

Figure 4.

Figure 4.

Mitochondrial protein levels and functional activity in A53T mice. A, Western blot analysis of Cox-I and ATP synthase levels in mitochondrial-enriched membrane fractions of spinal cord and frontal cortex of 11- to 12-month-old A53T mice and wt age-matched littermate controls. Protein staining detected with Ponceau S was used as a loading control. B, Graph showing the quantitative densitometric analysis of Cox-I and ATP synthase protein levels in A53T mice and wt age-matched controls. The values are mean ± SD. No differences were detected. C, Biochemical assay for Cox-I enzyme activity in the spinal cord and frontal cortex of 11- to 12-month-old A53T mice and wt age-matched littermate controls. The values are mean ± SD. *p < 0.01; significant difference from wt control.