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. 2019 Feb;69(1):35–47. doi: 10.30802/AALAS-CM-18-000025

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Figure 1. — Diagram of the timeline and procedures of the experiment. Rats were pair-housed in standard cages for 7 wk and underwent treatments daily (A). During week 5, a baseline blood sample was collected from each animal. During week 6, dermal punches were conducted to activate the immune response (B) During week 7, the 2 trials of the forced swim task were conducted over the course of 2 d, and a blood sample was collected (C). After 7 wk of treatment, neuroendocrine assessments were conducted, including hormone assays for dehydroepiandrosterone (DHEA), corticosterone (CORT), testosterone (T), oxytocin (OT), and the cytokines IL6 and IL10.