FIGURE 4.
Laboratory and tissue analysis of kidney recipients with graft failure in less than one week. (A) Creatinine shown for three recipients of this group showing elevation and graft failure by day 6. (B) Significant thrombocytopenia was developed in all recipients as shown by platelet count. (C) Severe anemia developed quickly in this subset of recipients as shown by hemoglobin levels during first week. (D) H&E stain at low and high magnification of representative tissue. Confocal microscopy of representative glomeruli showing, CD31 endothelial marker, C4d complement activation product, IgG and IgM binding. Significant IgM and C4d binding was noted in all grafts.
