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. 2019 Feb 20;14(2):e0211759. doi: 10.1371/journal.pone.0211759

Table 1. Expenditure on and access to antidiabetic, antihypertensive and antilipidemic drugs, FY 2010–2012.

Drug % share of OP drug expenditure
(FY 2010)
Quarterly change in drug recipients per 1,000 population* P-value No. of drug recipients per 1,000 population
2010
Q1
2010
Q3
2011
Q1
2011
Q3
2012
Q1
2012
Q3
Antidiabetics
    Insulin 3.0% 0.27 <0.0001 3.58 4.35 4.76 5.39 5.70 6.27
    Metformin 4.0% 0.53 <0.0001 15.81 18.29 19.31 19.39 20.57 21.37
    Glibenclamide 1.3% -0.20 <0.0001 11.08 10.46 10.38 9.43 9.59 9.15
    Glipizide 1.2% 0.55 <0.0001 4.03 5.78 6.77 7.51 8.42 9.54
    Pioglitazone 0.6% 0.14 <0.0001 0.75 1.16 1.46 1.67 1.86 2.08
    Overall 10.1% 0.63 <0.0001 21.70 24.58 25.88 26.06 27.58 28.75
Antihypertensive agents
    Amlodipine 2.5% 1.32 <0.0001 14.39 18.87 21.21 23.69 25.34 28.07
    Nifedipine 0.6% -0.04 0.0443 1.91 2.21 1.95 1.81 1.78 1.70
    Enalapril 2.3% 0.81 0.0002 20.52 24.54 26.40 27.03 27.72 29.31
    Losartan 0.5% 0.46 <0.0001 1.56 2.54 3.40 4.37 5.11 6.17
    Overall 5.9% 1.79 <0.0001 32.11 39.69 43.27 45.76 47.91 51.43
Antilipidemics
    Simvastatin 2.6% 1.51 <0.0001 20.84 25.39 29.02 31.54 33.67 35.73
    Atorvastatin 2.0% 0.03 0.0063 0.07 0.10 0.09 0.14 0.16 0.33
    Gemfibrozil 1.2% 0.26 0.001 6.87 8.36 9.27 8.80 9.69 9.51
    Fenofibrate 0.2% 0.04 0.0004 0.20 0.34 0.46 0.51 0.54 0.56
    Overall 6.0% 1.71 <0.0001 26.78 32.58 36.87 39.14 42.17 44.34

FY, fiscal year; OP, outpatient; Q, quarter

* based on time-series analysis of 12 quarters from Q1, FY 2010 to Q4, FY 2012