Table 3. Mean difference of dosages of osmolality and content of macronutrients and micronutrients analyzed between HM baseline and concentrates HMCI, HMC3m, and HMC6m.
| Variable | Comparisons | Mean difference |
95% CrI lower limit |
95% CrI upper limit |
|---|---|---|---|---|
| Energy (kcal/100 mL) |
HM baseline—HMCI | -23.680 | -25.910 | -21.450 |
| HM baseline—HMC3m | -20.690 | -22.930 | -18.410 | |
| HM baseline—HMC6m | -21.000 | -23.240 | -18.750 | |
| HMCI—HMC3m | 2.988 | 0.689 | 5.193 | |
| HMCI—HMC6m | 2.672 | 0.417 | 4.878 | |
| HMC3m - HMC6m | -0.316 | -2.598 | 1.951 | |
| Proteins (g/100 mL) |
HM baseline—HMCI | -0.576 | -0.668 | -0.482 |
| HM baseline—HMC3m | -0.490 | -0.584 | -0.394 | |
| HM baseline—HMC6m | -0.566 | -0.660 | -0.472 | |
| HMCI—HMC3m | 0.086 | -0.010 | 0.179 | |
| HMCI—HMC6m | 0.010 | -0.086 | 0.105 | |
| HMC3m - HMC6m | -0.076 | -0.174 | 0.018 | |
| Carbohydrates (g/100 mL) |
HM baseline—HMCI | -2.095 | -2.286 | -1.912 |
| HM baseline—HMC3m | -2.126 | -2.307 | -1.934 | |
| HM baseline—HMC6m | -2.099 | -2.286 | -1.912 | |
| HMCI—HMC3m | -0.030 | -0.220 | 0.151 | |
| HMCI—HMC6m | -0.004 | -0.189 | 0.176 | |
| HMC3m - HMC6m | 0.026 | -0.161 | 0.209 | |
| Total lipids (g/100 mL) |
HM baseline—HMCI | -1.437 | -1.678 | -1.193 |
| HM baseline—HMC3m | -1.095 | -1.340 | -0.845 | |
| HM baseline—HMC6m | -1.102 | -1.342 | -0.863 | |
| HMCI—HMC3m | 0.342 | 0.099 | 0.591 | |
| HMCI—HMC6m | 0.335 | 0.095 | 0.579 | |
| HMC3m - HMC6m | -0.006 | -0.248 | 0.233 | |
| Total solids (g/100 mL) |
HM baseline—HMCI | -4.004 | -4.307 | -3.703 |
| HM baseline—HMC3m | -3.715 | -4.020 | -3.406 | |
| HM baseline—HMC6m | -3.769 | -4.072 | -3.463 | |
| HMCI—HMC3m | 0.289 | -0.023 | 0.588 | |
| HMCI—HMC6m | 0.236 | -0.070 | 0.535 | |
| HMC3m - HMC6m | -0.053 | -0.363 | 0.254 | |
| True protein (g/100 mL) |
HM baseline—HMCI | -0.453 | -0.531 | -0.375 |
| HM baseline—HMC3m | -0.380 | -0.458 | -0.301 | |
| HM baseline—HMC6m | -0.444 | -0.522 | -0.366 | |
| HMCI—HMC3m | 0.072 | -0.008 | 0.149 | |
| HMCI—HMC6m | 0.008 | -0.070 | 0.085 | |
| HMC3m - HMC6m | -0.064 | -0.143 | 0.015 | |
| Osmolality (mOsm/Kg H20) |
HM baseline—HMCI | -162.200 | -177.900 | -146.600 |
| HM baseline—HMC3m | -166.200 | -182.000 | -150.300 | |
| HM baseline—HMC6m | -168.100 | -183.700 | -152.300 | |
| HMCI—HMC3m | -3.975 | -20.040 | 11.420 | |
| HMCI—HMC6m | -5.920 | -21.630 | 9.556 | |
| HMC3m - HMC6m | -1.945 | -17.880 | 13.980 | |
| Calcium (mg/100 mL) |
HM baseline—HMCI | -13.290 | -14.460 | -12.100 |
| HM baseline—HMC3m | -15.420 | -16.620 | -14.210 | |
| HM baseline—HMC6m | -17.390 | -18.580 | -16.200 | |
| HMCI—HMC3m | -2.139 | -3.356 | -0.971 | |
| HMCI—HMC6m | -4.103 | -5.325 | -2.904 | |
| HMC3m - HMC6m | -1.965 | -3.203 | -0.770 | |
| Magnesium (mEq/L) |
HM baseline—HMCI | -1.234 | -1.386 | -1.080 |
| HM baseline—HMC3m | -1.376 | -1.532 | -1.219 | |
| HM baseline—HMC6m | -1.591 | -1.747 | -1.437 | |
| HMCI—HMC3m | -0.141 | -0.298 | 0.010 | |
| HMCI—HMC6m | -0.357 | -0.515 | -0.201 | |
| HMC3m - HMC6m | -0.216 | -0.377 | -0.061 | |
| Sodium (mg/L) |
HM baseline—HMCI | -86.600 | -113.500 | -58.860 |
| HM baseline—HMC3m | -108.600 | -136.600 | -80.480 | |
| HM baseline—HMC6m | -97.060 | -124.900 | -69.270 | |
| HMCI—HMC3m | -22.020 | -50.450 | 5.252 | |
| HMCI—HMC6m | -10.460 | -38.880 | 17.470 | |
| HMC3m - HMC6m | 11.570 | -17.490 | 39.240 | |
| Potassium (mg/L) |
HM baseline—HMCI | -392.100 | -451.100 | -331.600 |
| HM baseline—HMC3m | -393.000 | -453.600 | -330.500 | |
| HM baseline—HMC6m | -523.400 | -584.100 | -462.800 | |
| HMCI—HMC3m | -0.929 | -62.620 | 58.190 | |
| HMCI—HMC6m | -131.400 | -193.500 | -70.690 | |
| HMC3m - HMC6m | -130.400 | -193.400 | -69.810 | |
| Copper (μg/100 mL) |
HM baseline—HMCI | -14.950 | -18.200 | -11.740 |
| HM baseline—HMC3m | -7.799 | -11.040 | -4.511 | |
| HM baseline—HMC6m | -5.914 | -9.141 | -2.656 | |
| HMCI—HMC3m | 7.154 | 3.840 | 10.330 | |
| HMCI—HMC6m | 9.040 | 5.782 | 12.230 | |
| HMC3m - HMC6m | 1.885 | -1.388 | 5.166 | |
| Zinc (μg/100 mL) |
HM baseline—HMCI | -54.530 | -79.040 | -30.160 |
| HM baseline—HMC3m | -74.840 | -99.420 | -49.910 | |
| HM baseline—HMC6m | -101.800 | -126.400 | -77.040 | |
| HMCI—HMC3m | -20.320 | -45.420 | 3.872 | |
| HMCI—HMC6m | -47.290 | -72.040 | -23.100 | |
| HMC3m - HMC6m | -26.980 | -51.910 | -2.026 | |
| Phosphorus (mg/100 mL) |
HM baseline—HMCI | -3.859 | -5.557 | -2.176 |
| HM baseline—HMC3m | -5.741 | -7.437 | -4.020 | |
| HM baseline—HMC6m | -5.881 | -7.575 | -4.175 | |
| HMCI—HMC3m | -1.882 | -3.618 | -0.209 | |
| HMCI—HMC6m | -2.022 | -3.738 | -0.355 | |
| HMC3m - HMC6m | -0.140 | -1.865 | 1.570 |
HM baseline: Human milk baseline; HMCI: HM concentrated for immediate analysis; HMC3m: HM concentrate for analysis after 3 months of storage; HMC6m: HM concentrate for analysis after 6 months of storage. 95% CrI: Credibility interval 95%.