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. 2019 Feb 20;14(2):e0212486. doi: 10.1371/journal.pone.0212486

Fig 5. Effect of acute DOX administration on BAX gene expression.

Fig 5

Kidneys were harvested from male or female C57Bl/6 mice (A) 1 day (n = 8 per group), (B) 3 days (n = 4–5 per group), or (C) 6 days (n = 4–6 per group) following the administration of 20 mg/kg DOX or equivalent volume of sterile saline and total RNA was prepared. BAX gene expression was determined by real-time PCR. Values were normalized to beta-actin and expressed relative to male control of the same time point. Values are expressed as mean ± SEM. * P < 0.05, compared to saline-treated mice of the same sex; # P < 0.05, compared to male mice of the same treatment by Tukey’s post-hoc analysis.