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. 2019 Feb 20;14(2):e0212436. doi: 10.1371/journal.pone.0212436

Table 2. Sociodemographic and clinical characteristic of the participants according to fitness level.

Fexibility Strength CRF
Back Scratch Test Handgrip 30-sec chair stand 6-min walk test
Low High   Low High   Low High   Low High  
(n = 35) (n = 35) (n = 35) (n = 35) (n = 35) (n = 35) (n = 27) (n = 22)
mean mean p mean mean p mean mean p mean mean p
Age (years) 46.0 (14.2) 39.0 (12.9) 0.037 44.1 (15.8) 40.9 (11.7) 0.353 50.1 (13.1) 34.9 (10.1) <0.001 46.8 (14.3) 34.7 (9.9) 0.002
Weight (kg) 67.3 (14.0) 63.6 (7.1) 0.173 64.1 (9.7) 66.8 (12.5) 0.311 67.4 (11.5) 63.5 (10.7) 0.153 69.6 (15.4) 62.4 (6.7) 0.049
Body mass index (kg/m2) 26.9 (5.5) 24.1 (3.1) 0.01 25.7 (4.2) 25.4 (5.1) 0.775 26.4 (4.6) 24.6 (4.5) 0.105 28.4 (5.8) 23.2 (1.6) <0.001
Disease duration (years) 15.0 (10.1) 11.9 (9.9) 0.192 15.9 (10.7) 11.0 (8.7) 0.042 16.5 (11.0) 10.4 (8.0) 0.009 14.7 (10.0) 8.0 (6.8) 0.01
SLEDAI (0–105) 0.69 (1.5) 0.8 (1.6) 0.763 0.7 (1.5) 0.7 (1.6) 1.000 1.0 (1.8) 0.5 (1.2) 0.128 1.1 (1.9) 1.0 (1.6) 0.831
Systemic Damage Index for SLE
(0–46)
0.49 (1.0) 0.5 (1.0) 0.902 0.7 (1.2) 0.2 (0.6) 0.017 0.8 (1.2) 0.2 (0.4) 0.008 0.7 (1.1) 0.2 (0.4) 0.057
Current corticoicorteroids intake
(yes, %)
22 (62.9) 23 (65.7) 1.000 24 (68.6) 21 (60.0) 0.618 22 (62.9) 23 (65.7) 1.000 17 (63.0) 16 (72.7) 0.549
Daily corticorteroids dose (mg/day) 4.1 (5.6) 3.6 (4.1) 0.649 4.6 (6.0) 3.0 (3.3) 0.169 3.9 (5.6) 3.8 (4.1) 0.976 4.4 (6.1) 3.8 (3.1) 0.682
Cumulative corticorteroids exposure
(last 3 years) mg
2368.2 (2477.4) 3299.9 (2879.3) 0.154 3407.6 (2956.3) 2230.0 (2310.5) 0.07 2490.0 (2651.7) 3174.5 (2752.8) 0.297 2445.1 (2593.7) 3185.4 (2784.6) 0.341
Hydroxychloroquine intake 31 (88.6) 31 (88.6) 1.000 30 (85.7) 32 (91.4) 0.71 30 (85.7) 32 (91.4) 0.71 24 (88.9) 21 (95.5) 0.617
(yes, %)
Daily hydroxychloroquine dose (mg/day) 197.2 (122.0) 195.9 (113.9) 0.965 185.3 (113.3) 207.8 (121.5) 0.427 186.1 (120.1) 206.9 (114.9) 0.462 188.9 (111.1) 241.5 (119.5) 0.117
Immunosuppressants 15 (42.9) 18 (51.4) 0.632 19 (54.3) 14 (40.0) 0.338 13 (37.1) 20 (57.1) 0.15 10 (37.0) 11 (50.0) 0.398
(current intake) (yes, %)
Immunosuppressants 14 (40.0) 16 (45.7) 0.809 18 (51.4) 12 (34.3) 0.227 11 (31.4) 19 (54.3) 0.09 9 (33.3) 11 (50.0) 0.26
(previous intake) (yes, %)
Organ involvement (yes, %)      
    Joint involvement 26 (74.3) 24 (68.6) 0.792 25 (71.4) 25 (71.4) 1.000 28 (80.0) 22 (62.9) 0.185 17 (63.0) 14 (63.6) 1.000
    Neurological involvement 2 (5.7) 4 (11.4) 0.428 3 (8.6) 3 (8.6) 1.000 5 (14.3) 1 (2.9) 0.198 2 (7.4) 2 (9.1) 1.000
BDI-II total score (0–63) 10.60 (8.0) 12.9 (9.8) 0.284 11.0 (9.2) 12.5 (8.8) 0.484 11.4 (8.2) 12.1 (9.7) 0.742 13.9 (8.9) 12.1 (9.8) 0.515
MFI general fatigue (0–20) 13.57 (4.9) 13.3 (3.4) 0.757 13.3 (4.7) 13.5 (3.7) 0.888 13.7 (4.4) 13.1 (4.1) 0.518 14.3 (4.3) 13.3 (4.3) 0.453

Values are mean (SD) unless otherwise is indicated

An independent t test and χ2 test were used to compare variables between groups

Low and high fitness level according to the median value for flexibility (1.35 cm in the back scratch test), upper body strength (28.28 kg/cm2 in the handgrip test), lower body strength (15 repetitions in the 30-sec chair stand test) and cardiorespiratory fitness (CRF; 575 m in the 6-min walk test).