Table 3. Comparison of biomarker concentrations (pg/ml) based on clinical evolution from initial examination(T1) to final exam (T2).
| MP | PI | |||||
|---|---|---|---|---|---|---|
| T1 (MP) | T2 (MP) | T1 (MP) | T2 (PI) | |||
| Mean (SD) | Mean (SD) | p | Mean (SD) | Mean (SD) | p | |
| IL-1β | 17797.7 (25025.3) | 21470.7 (25193.4) | 0.217 | 21468.0 (23332.9) | 42689.5 (116502.6) | 0.506 |
| IL-10 | 4.4 (11.7) | 4.5 (11.1) | 0.678 | 8.2 (18.3) | 7.4 (17.7) | 0.866 |
| TNF-α | - | 1.2 (7.9) | - | 12.4 (22.7) | 10.9 (21.5) | 0.999 |
| TGF-β | 9.9 (24.6) | 5.8 (10.4) | 0.661 | 5.4 (9.4) | 10.6 (24.0) | 0.386 |
| MMP-2 | 14.8 (14.3) | 18.4 (27.2) | 0.673 | 25.4 (39.3) | 41.1 (104.7) | 0.677 |
| RANK | 22.2 (18.7) | 21.4 (20.2) | 0.554 | 26.4 (15.1) | 24.4 (17.6) | 0.357 |
GNTP: group without periodontal/peri-implant maintenance; GTP: group with periodontal/peri-implant maintenance. IL: Interleukin; TNF: tumor necrosis factor; TGF: transforming growth factor; MMP: metalloproteinase; RANK: Receptor activator of nuclear factor kappa; OPG: Osteoprotegerin; n: individuals; MP: peri-implant mucositis; PI: peri-implantitis; SD standard deviation