Table 3. Growth failure at adult final height in patients with pediatric onset IBD.
Authors | Year | Disease | Number of patients | Definition of growth failure | Percentage of growth failure |
---|---|---|---|---|---|
Markowitz et al. | 1993 | IBD | 48 | Final height <2 centiles | 19% |
Griffiths et al. | 1993 | CD | 67 | Final height <−2 SD | 25% |
Hildebrand et al. | 1994 | IBD | 110 | Final height < target height | 36% of CD |
Sawczenko et al. | 2006 | CD | 123 | Target height >8 cm below target height | 19% |
Vasseur et al. | 2010 | CD | 261 | Final height <−2 SD | 7% |
Lee et al. | 2010 | IBD | 108 | Final height <−1.64 SD | 11% |
Ley et al. | 2010 | CD | 75 | Final height <−2 SD | 5% |
Current study | 2018 | CD | 2,678 | Height z-score <−2 | 6% |
UC | 3,775 | Height z-score <−2 | 5% |
IBD, inflammatory bowel disease; CD, Crohn’s disease; UC, ulcerative colitis; SD, standard deviation.