Figure 3:

Spatial resolution and sensitivity of hydrogel-based proteomic workflows: A) Using dermal punch biopsy tools, hydrogels can be fabricated down to ~260 µm in diameter. B) Extracting peptides using a hydrogel with a diameter of 777 µm, the white matter and molecular layers of rat brain cerebellum were profiled and the proteomic profiles were compared. Figure 3 was adapted from reference [54].