Table 1.
Univariate and multivariate analysis of markers of HIV-1 acquisition among vaccinees
| Univ. OR (95% CI) | Univ. p | Multiv. OR (95% CI) | Multiv. p | |
|---|---|---|---|---|
| IgA antibodies binding to Env | 1.54 [1.06, 2.26] | 0.0237 | 1.22 [0.733, 2.02] | 0.432 |
| IgG antibodies binding to V1/V2 | 0.703 [0.446, 1.07] | 0.112 | 1.24 [0.670, 2.29] | 0.485 |
| DQB1*06 | 1.12 [0.408, 2.78] | 0.819 | 0.505 [0.0297, 2.75] | 0.517 |
| Interaction IgA:DQB1*06 | – | – | 9.77 [1.95, 112] | 0.0216 |
| DPB1*13 | 0.696 [0.270, 1.64] | 0.426 | 0.453 [0.0975, 1.53] | 0.243 |
| Interaction IgG:DPB1*13 | – | – | 0.132 [0.0216, 0.537] | 0.0115 |
| PFS | 0.620 [0.390, 0.944] | 0.0322 | 0.477 [0.252, 0.844] | 0.0153 |
| INTERFERON_GAMMA_RESPONSE | 0.883 [0.803, 0.967] | 0.00837 | 0.974 [0.857, 1.10] | 0.677 |
| MTORC1_SIGNALING | 1.33 [1.15, 1.57] | 0.000336 | 1.25 [1.01, 1.56] | 0.0496 |
| TNFA_SIGNALING_VIA_NFKB | 1.24 [1.10, 1.42] | 0.000871 | 1.08 [0.919, 1.28] | 0.368 |
For each variable, the odds ratio (OR) and its 95% confidence interval (CI) is reported per one standard deviation increase. The p value of a z-test testing that the OR is different from 1 is reported in the table. p values inferior or equal 0.05 are indicated in bold. All univariate (univ.) and multivariate (multiv.) logistic regression models were adjusted for gender and behavior risk of the participants