Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 20;10(3):175. doi: 10.1038/s41419-019-1382-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Scatter plot. Green lines represent fold-change. Above line 1 and below line 3 indicate >1.5-fold-change in circRNA expression level in TNBC (N = 4) as compared to NMGT (N = 3). b Volcano plot. The vertical green lines correspond to 1.5-fold upregulated and downregulation, and the horizontal green line represents p value of 0.05. The red points in the plot represent circRNAs with statistically significant differential expression. c circRNAs profile for TNBC and LA (N = 4) subtypes as compared to NMGT. d Clustered heatmap for differentially expressed circRNAs. Rows represent circRNAs and columns represent tissue types. circRNAs were classified according to the Pearson correlation. The color scale runs from green (low intensity) to black (medium intensity), to red (strong intensity). e Network of 215 differentially expressed circRNAs and the predicted target miRNAs in TNBC. Nodes are represented in different colors: red for upregulated circRNAs, yellow for downregulated circRNAs, and blue for predicted miRNA sponge circRNAs. f Relative downregulated expression of circRNAs by microarray data and quantitative reverse transcription polymerase reaction (qRT-PCR) in TNBC