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. 2019 Feb 20;9:2358. doi: 10.1038/s41598-019-38865-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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NanoString analysis of enzyme and receptor transcripts in intestinal mucosal biopsies. Graphs showing fold changes (decrease/increase) of mRNA of enzymes and receptors of the ECS and the endocannabinoidome in intestinal mucosal biopsies of patients with ulcerative colitis (UC) (a) and Crohn’s disease (CD) (b) in comparison to biopsies from control subjects. n = 9–11; One-Way ANOVA was performed between sample groups. Genes with p values < 0.05 and fold changes of at least 1.5 were considered to be significantly regulated (marked by asterisks *). See p values of each target in Supplementary Table S1.