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. 2019 Feb 20;9:2320. doi: 10.1038/s41598-019-38568-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Impaired cell cycle progression in mice with defective Brg1. (A) GSEA enrichment plot for the cell cycle pathway. GSEA analysis was conducted for detecting differences between the Brg1 KO and the Control group at 48 h post PH. The cell cycle pathway is significantly associated with the Brg1 KO genotype (FDR = 0.0003). (B–D) Protein expression of Cyclin B1 and Cdk1 in the liver after PH was analysed by Western blot. Representative gels (B) and densitometric analyses (C,D) are depicted, n > 3.