Table 2.
Bone parameters | Cre- | Cre+ | P value | ||||
---|---|---|---|---|---|---|---|
Female | Male | Female | Male | Female | Male | ||
Trabecular bone analysis | (Tb.BV/TV)/% | 0.083 ± 0.013 | 0.088 ± 0.023 | 0.112 ± 0.031 | 0.127 ± 0.034 | 0.093 | 0.116 |
Tb.N/µm-1 | 1.773 ± 0.252 | 4.175 ± 0.473 | 2.406 ± 0.568 | 3.953 ± 0.366 | 0.052 | 0.487 | |
Tb.Th/µm | 0.045 ± 0.002 | 0.044 ± 0.002 | 0.045 ± 0.004 | 0.054 ± 0.006 | 0.843 | *0.024 | |
Tb.Sp/µm | 0.438 ± 0.235 | 0.238 ± 0.030 | 0.389 ± 0.102 | 0.247 ± 0.026 | 0.678 | 0.676 | |
Cortical bone analysis | (Ct.BV/TV)/% | 0.916 ± 0.003 | 0.915 ± 0.006 | 0.915 ± 0.004 | 0.915 ± 0.002 | 0.790 | 0.977 |
Ct.Th/µm | 0.212 ± 0.002 | 0.211 ± 0.014 | 0.208 ± 0.003 | 0.210 ± 0.009 | 0.100 | 0.870 | |
Body Weight | Gram | 31.70 ± 2.574 | 28.00 ± 3.317 | 31.75 ± 2.111 | 26.26 ± 2.353 | 0.977 | 0.367 |
No significant differences were observed between control Cre–, mice, compared to Sost-CreERT2 mice/tdTomato, of the same gender using unpaired Student’s t-test *P < 0.05