Skip to main content
. 2019 Feb 21;7:6. doi: 10.1038/s41413-018-0037-4

Table 2.

Micro CT analysis of trabecular bone and cortical bone in tibia and whole body weight. (n = 4–5)

Bone parameters Cre- Cre+ P value
Female Male Female Male Female Male
Trabecular bone analysis (Tb.BV/TV)/% 0.083 ± 0.013 0.088 ± 0.023 0.112 ± 0.031 0.127 ± 0.034 0.093 0.116
Tb.N/µm-1 1.773 ± 0.252 4.175 ± 0.473 2.406 ± 0.568 3.953 ± 0.366 0.052 0.487
Tb.Th/µm 0.045 ± 0.002 0.044 ± 0.002 0.045 ± 0.004 0.054 ± 0.006 0.843 *0.024
Tb.Sp/µm 0.438 ± 0.235 0.238 ± 0.030 0.389 ± 0.102 0.247 ± 0.026 0.678 0.676
Cortical bone analysis (Ct.BV/TV)/% 0.916 ± 0.003 0.915 ± 0.006 0.915 ± 0.004 0.915 ± 0.002 0.790 0.977
Ct.Th/µm 0.212 ± 0.002 0.211 ± 0.014 0.208 ± 0.003 0.210 ± 0.009 0.100 0.870
Body Weight Gram 31.70 ± 2.574 28.00 ± 3.317 31.75 ± 2.111 26.26 ± 2.353 0.977 0.367

No significant differences were observed between control Cre, mice, compared to Sost-CreERT2 mice/tdTomato, of the same gender using unpaired Student’s t-test *P < 0.05