Table 2.
Bacterial inhibitory concentration and relative bacterial inhibitory concentration values from activity measurements of wild type combinations of Pls-α, Pls-β, Mur-α and Mur-β.
| Peptide combinationb | Bacterial inhibitory concentration (nM) | Relative bacterial inhibitory concentration valuesa | ||
|---|---|---|---|---|
| Lac. lactis IL1403 | Lab. sakei NCFB 2714 | Lac. lactis IL1403 | Lab. sakei NCFB 2714 | |
| Pls-α | >1000 | 91 ± 5 | >1500 | 650 |
| Pls-β | >1000 | >1000 | >1500 | >7000 |
| Mur-α | >1000 | >1000 | >1500 | >7000 |
| Mur-β | >1000 | 670 ± 120 | >1500 | 5000 |
| Pls-α + Pls-β | 0.7 ± 0.2 | 0.14 ± 0.02 | 1 | 1 |
| Mur-α + Mur-β | 2.1 ± 0.4 | 0.23 ± 0.06 | 3 | 2 |
| Pls-α + Mur-α | >1000 | 26 ± 5 | >1400 | 200 |
| Pls-α + Mur-β | 2.2 ± 0.3 | 0.63 ± 0.01 | 3 | 5 |
| Pls-β + Mur-α | 3.2 ± 0.7 | 0.63 ± 0.01 | 5 | 5 |
| Pls-β + Mur-β | >1000 | 270 ± 120 | >1400 | 2000 |
aThe relative bacterial inhibitory concentration is defined as a fold increase or decrease in activity compared to the wild type combination of Pls-α and Pls-β.