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. 2019 Jan 12;116(4):670–683. doi: 10.1016/j.bpj.2019.01.009

Figure 5.

Figure 5

Frequently used cancer cell lines undergo durotaxis. (A) FMI values for U87, T98G, MDA-MB-231, and HT1080 cells on soft, medium, and stiff regions of the stiffness gradient. (B) Corresponding angular displacement values for each of the cancer cell populations occupying the soft portion of the gradient. Error bars represent mean ± SE for n = 255, n = 800, n = 495, and n = 136 cells from 3, 3, 2, and 2 biological replicates in independent experiments, respectively. FMI was evaluated statistically by one-way ANOVA and Tukey’s post hoc test (∗p ≤ 0.05, ∗∗∗p ≤ 0.001). Angular displacement was evaluated using Rayleigh tests (∗∗∗p ≤ 0.001). To see this figure in color, go online.