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. 2019 Jan 30;39(5):929–943. doi: 10.1523/JNEUROSCI.1377-18.2018

Figure 8.

Figure 8.

Single acute administration of l-DOPA restores extracellular DA levels in NAc shell of EtOH-withdrawn rats. a, EtOH-WDL (12 h) rats displayed lower levels of dialysate DA in the NAc shell, with respect to CTRL rats; l-DOPA/BENSERAZIDE (6/6 mg/kg, s.c.) administration significantly increased DA levels in the NAc shell of EtOH-WDL (12 h) rats, up to CTRL's levels. b, Notably, l-DOPA induced a larger increase of dialysate DA in the NAc shell of EtOH-WDRL (12 h) compared with basal (filled symbol) and to dialysate DA in the NAc shell of CTRL rats expressed as percentage of baseline. Each value represents the mean ± SEM; n = 4 rats. **p < 0.01, ***p < 0.01.