TABLE 2.

List of model parameters along with their numerical values and sources

Parameter	Description (unit)	Estimate	CV%
Jlung	Transmigration rate for each tissue (1/h)	1843.0	15.4
Jheart		34.9	17.2
Jkidney		87.3	37.9
Jbrain		1.4	21.2
Jmuscle		0.5	19.7
Jbone		82.6	16.7
Jtumor		0.6	18.6
Jskin		0.6	18.7
Jfat		1.6	18.5
JSI		12.9	17.1
JLI		5.2	18.1
Jspleen		114.0	33.8
Jliver		126.9	18.9
Jpancreas		10.0	20.0
Jother		86.8	17.7
Rkidney	Retention factor	3.9	37.9
Rspleen		9.8	34.8
Rliver		2.5	18.4
Elung	Elimination rate (1/h)	0.84	Fixed (Zhu et al., 1996)
Ftissue	Fraction of T cells recirculated to lymph node	1	Fixed (assumption)
Qtissue, Ltissue, Vtissue	Physiologic blood flows, lymph flows, and tissue volumes for each mouse tissue (ml/h, ml/h, ml)		Fixed (Shah and Betts, 2012)
Qtumor	Tumor blood flow (ml/h)	6	Fixed (Zhu et al., 1996)
Vtumor	Tumor volume (ml or g)	0.45	Fixed (radius∼3.85 mm)