Figure 3.

Vector Distribution in the Muscle and Estimated Total Vector Genomes in the Lower Extremity

(A) Heatmap of distribution of vector genomes in the muscle of both the dosed and undosed limbs 60 days post-delivery. IM, intramuscular; IAPD, intra-arterial push and dwell; VLP, venous limb perfusion. n = 2 per group. (B) Total vector genomes delivered to the targeted rhesus lower extremity muscle, as estimated based on the volume of muscle tissue perfused and the nuclear density of muscle tissue.