Table 2.
Gastric lipid peroxidation, glutathione contents, CAT, and SOD activities in the intact or IND-treated rats
Items (Unit) groups | Lipid peroxidation (nM of MDA/g tissue) | Glutathione contents (nM/mg tissue) | Enzyme activity | |
---|---|---|---|---|
CAT (mM/min /g tissue) | SOD (mM/min/mg tissue) | |||
Control | ||||
Intact | 2.73 ± 1.15 | 5.21 ± 1.34 | 87.75 ± 17.29 | 151.50 ± 16.58 |
IND | 20.02 ± 3.60a | 1.49 ± 0.22d | 174.25 ± 26.86a | 75.75 ± 12.63a |
Reference | ||||
OM 10 mg kg− 1 | 12.91 ± 2.96ac | 2.37 ± 0.42d,e | 126.63 ± 14.92a,c | 113.88 ± 10.74a,c |
FBe treated as | ||||
100 mg kg− 1 | 15.56 ± 1.95a,c | 2.05 ± 0.34d,e | 142.13 ± 13.42a,c | 100.38 ± 18.91a,c |
200 mg kg− 1 | 13.01 ± 2.16a,c | 2.56 ± 0.68d,e | 124.75 ± 19.31a,c | 115.00 ± 11.99a,c |
300 mg kg− 1 | 6.11 ± 1.79a,c | 3.37 ± 0.54d,e | 109.63 ± 16.40b,c | 131.00 ± 15.15a,c |
Values are expressed as mean ± S.D. of eight rats
FBe triple fermented barley extract as test material, IND indomethacin, OM omeprazole, MDA malondialdehyde, CAT catalase, SOD superoxide dismutase
ap < 0.01
bp < 0.05 as compared with intact control by LSD test
cp < 0.01 as compared with IND control by LSD test
dp < 0.01 as compared with intact control by MW test
ep < 0.01 as compared with IND control by MW test